[(1R,5S)-5-[dimethyl(phenyl)silyl]-2-(hydroxymethyl)cyclopent-2-en-1-yl]methanediol - Names and Identifiers
Name | (1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid
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Synonyms | EOS-61484 5-[dimethyl(phenyl)silyl]-2-(hydroxymethyl)-1-cyclopent-2-enecarboxylic acid (5S)-5-(dimethyl(phenyl)silyl)-2-(hydroxymethyl)cyclopent-2-enecarboxylic acid trans-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid (5S)-5-(dimethyl(phenyl)silyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylic acid (1R,5S)-5-(Dimethylphenylsilyl)-2-(hydroxymethyl)-2-cyclopentene-1-carboxylic acid (1R,5S)-5-(dimethyl(phenyl)silyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylicacid [(1R,5S)-5-[dimethyl(phenyl)silyl]-2-(hydroxymethyl)cyclopent-2-en-1-yl]methanediol 2-Cyclopentene-1-carboxylic acid,5-(dimethylphenylsilyl)-2-(hydroxymethyl)-,(1R,5S)-
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CAS | 649761-21-7
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EINECS | 1806241-263-5 |
InChI | InChI=1/C15H22O3Si/c1-19(2,12-6-4-3-5-7-12)13-9-8-11(10-16)14(13)15(17)18/h3-8,13-18H,9-10H2,1-2H3/t13-,14-/m0/s1 |
[(1R,5S)-5-[dimethyl(phenyl)silyl]-2-(hydroxymethyl)cyclopent-2-en-1-yl]methanediol - Physico-chemical Properties
Molecular Formula | C15H20O3Si
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Molar Mass | 276.4 |
Density | 1.14 |
Boling Point | 433.3±45.0 °C(Predicted) |
Flash Point | 209.1°C |
Vapor Presure | 7.03E-08mmHg at 25°C |
pKa | 4.50±0.60(Predicted) |
Refractive Index | 1.569 |
[(1R,5S)-5-[dimethyl(phenyl)silyl]-2-(hydroxymethyl)cyclopent-2-en-1-yl]methanediol - Introduction
(1R,5S)-5-(Dimethylphenylsilyl)-2-hydroxymethyl-2-cyclopentene-1-carboxylic acid is an organic compound with the following properties:
-Appearance: Colorless liquid or solid
-Molecular formula: C15H20O3Si
-Molecular weight: 276.41g/mol
-Melting point: about 40-42°C
-Boiling point: about 330°C
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide
(1R,5S)-5-(dimethylphenylsilyl)-2-hydroxymethyl-2-cyclopentene-1-carboxylic acid is mainly used in organic synthesis as a catalyst, reaction intermediate or pharmaceutical synthesis raw material.
The method for preparing (1R,5S)-5-(dimethylphenylsilyl)-2-hydroxymethyl-2-cyclopentene-1-carboxylic acid is generally carried out by the following steps:
1.2-Methyl -2-cyclopentene -1-one was obtained as a raw material.
2. 2-Methyl-2-cyclopenten-1-one is reacted with trimethylfluorosilane by heating reaction to obtain 2-methyl-5-trimethylsilyl-2-cyclopenten-1-one.
3. A reaction characterized by redox is carried out under alkaline conditions to obtain (1R,5S)-5-(dimethylphenylsilyl)-2-cyclopentene-1-carboxylic acid from 2-methyl-5-trimethylsilyl-2-cyclopentene-1-one.
Regarding safety information,(1R,5S)-5-(dimethylphenylsilyl)-2-hydroxymethyl-2-cyclopentene-1-carboxylic acid is irritating and should be used to avoid direct contact with skin, eyes and respiratory tract. Operate in a well-ventilated area and wear appropriate protective equipment.
Last Update:2024-04-09 20:02:46